Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Cyp1b1tm1Gonz
Name:	cytochrome P450, family 1, subfamily b, polypeptide 1; targeted mutation 1, Frank J Gonzalez
MGI ID:	MGI:2154690
Synonyms:	cyp1b1-
Gene:	Cyp1b1  Location: Chr17:80014369-80022490 bp, - strand  Genetic Position: Chr17, 50.3 cM
Alliance:	Cyp1b1tm1Gonz page

Germline Transmission:	Earliest citation of germline transmission: J:53827
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin selection cassette was inserted into coding sequences in exon 3. (J:53827)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

List all tumor models in MMHCdb carrying Cyp1b1tm1Gonz

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Cyp1b1 Mutation:	26 strains or lines available

Original:	J:53827 Buters JT, et al., Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1977-82
All:	46 reference(s)