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Slc2a10 Gene Detail
Summary
  • Symbol
    Slc2a10
  • Name
    solute carrier family 2 (facilitated glucose transporter), member 10
  • Synonyms
    Glut10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156687
    NCBI Gene: 170441
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:165345817-165361837 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156687
 protein coding gene Chr2:165345707-165361837 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026896
 protein coding gene Chr2:171069825-171083804 (+)
A/J MGP_AJ_G0026862
 protein coding gene Chr2:164061094-164075145 (+)
AKR/J MGP_AKRJ_G0026835
 protein coding gene Chr2:168952107-168968768 (+)
BALB/cJ MGP_BALBcJ_G0026871
 protein coding gene Chr2:164417537-164432502 (+)
C3H/HeJ MGP_C3HHeJ_G0026615
 protein coding gene Chr2:169298016-169313312 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027319
 protein coding gene Chr2:176020204-176035652 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024691
 protein coding gene Chr2:157460274-157472439 (+)
CAST/EiJ MGP_CASTEiJ_G0026073
 protein coding gene Chr2:169733423-169751293 (+)
CBA/J MGP_CBAJ_G0026592
 protein coding gene Chr2:182421509-182442828 (+)
DBA/2J MGP_DBA2J_G0026728
 protein coding gene Chr2:163216669-163233254 (+)
FVB/NJ MGP_FVBNJ_G0026696
 protein coding gene Chr2:161661288-161677374 (+)
LP/J MGP_LPJ_G0026830
 protein coding gene Chr2:171111422-171127016 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026715
 protein coding gene Chr2:185942629-185958324 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027375
 protein coding gene Chr2:168844630-168863942 (+)
PWK/PhJ MGP_PWKPhJ_G0025808
 protein coding gene Chr2:162827839-162839229 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025610
 protein coding gene Chr2:167760765-167776633 (+)
WSB/EiJ MGP_WSBEiJ_G0026144
 protein coding gene Chr2:169735964-169749776 (+)



Homology
more
  • Human Ortholog
    SLC2A10, solute carrier family 2 member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC2A10, solute carrier family 2 member 10
  • Synonyms
    ATORS, ATS, GLUT10
  • Links
    NCBI Gene ID: 81031
    neXtProt AC: NX_O95528
    UniProt: O95528

  • Chr Location
    20q13.12; chr20:46708320-46736347 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC2A10 associations

Human Disease Mouse Models
      
IDs
 View 2 "NOT" models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice carrying ENU-induced mutations in this gene display thickening and aberrant vessel wall shape of large and medium size arteries, with significantly increased elastic fiber number and size. Cerebral arteries appear normal with no evidence of tortuosity, stenosis/dilatation or aneurysm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    45
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    11
  • cDNA Data
    11
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 170441 NCBI Gene Model | MGI Sequence Detail 16021 C57BL/6J ±  kb
    transcript NM_130451 RefSeq | MGI Sequence Detail 3434 ZRU/MplStud  
    polypeptide Q8VHD6 UniProt | EBI | MGI Sequence Detail 536 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000015059 solute carrier family 2, facilitated glucose transporter member 10
      (term hierarchy)
    • InterPro Domains
      IPR005828 Major facilitator, sugar transporter-like
      IPR020846 Major facilitator superfamily domain
      IPR050820 Major Facilitator Superfamily Sugar Transporter
      IPR036259 MFS transporter superfamily
      IPR003663 Sugar/inositol transporter
      IPR005829 Sugar transporter, conserved site
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1858383
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:49040 Herron BJ, et al., Putative assignment of ESTs to the genetic map by use of the SSLP database. Mamm Genome. 1998 Dec;9(12):1072-4
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory