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Zic1tm1Jaru
Targeted Allele Detail
Summary
Symbol: Zic1tm1Jaru
Name: zinc finger protein of the cerebellum 1; targeted mutation 1, Jun Aruga
MGI ID: MGI:2156822
Gene: Zic1  Location: Chr9:91240111-91247863 bp, - strand  Genetic Position: Chr9, 48.26 cM
Alliance: Zic1tm1Jaru page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73794
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector containing a neo cassette replaced the first exon containing the start codon and encoding three of the five zinc fingers. (J:73794)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 33 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zic1 Mutation:  32 strains or lines available
References
Original:  J:73794 Aruga J, et al., Mouse Zic1 is involved in cerebellar development. J Neurosci. 1998 Jan 1;18(1):284-93
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory