Mafb<m1Gsb> Chemically induced Allele Detail MGI Mouse (MGI:2157803)

Mafb^m1Gsb
Chemically induced Allele Detail

Summary

Symbol:	Mafb^m1Gsb
Name:	MAF bZIP transcription factor B; mutation 1, Gregory S Barsh
MGI ID:	MGI:2157803
Synonyms:	kreisler^enu, kr^ENU, MafB^ENU
Gene:	Mafb Location: Chr2:160205623-160208985 bp, - strand Genetic Position: Chr2, 80.92 cM
Alliance:	Mafb^m1Gsb page

Mutation
origin

Strain of Origin:

(BALB/cJ x SJL/J)F1

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		Mutation details: An A-to-G transition at nucleotide 743 resulted in an asparagine to serine substitution at amino acid 248. The mutation is in the putative DNA-binding domain and is conserved among other gene family members. (J:22020)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

27 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Mafb Mutation:	20 strains or lines available

References

Original:	J:22020 Cordes SP, et al., The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 1994 Dec 16;79(6):1025-34
All:	5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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