Bax<tm1Dlo> Targeted Allele Detail MGI Mouse (MGI:2158306)

Bax^tm1Dlo
Targeted Allele Detail

Summary

Symbol:	Bax^tm1Dlo
Name:	BCL2-associated X protein; targeted mutation 1, Dennis Y Loh
MGI ID:	MGI:2158306
Synonyms:	bax-
Gene:	Bax Location: Chr7:45111121-45116322 bp, - strand Genetic Position: Chr7, 29.32 cM, cytoband B5
Alliance:	Bax^tm1Dlo page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:39573
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		A 5.6 kb genomic fragment containing exons 2-6 was replaced with a neomycin selection cassette. (J:39573)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Bax Mutation:	24 strains or lines available

Notes

This allele is described in the materials and methods of the above listed reference as a gift from D. Y. Loh, but it was not independently published.

References

Original:	J:39573 Shindler KS, et al., Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice. J Neurosci. 1997 May 1;17(9):3112-9
All:	8 reference(s)

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