Bcl6tm1Sdt
Targeted Allele Detail
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| Symbol: |
Bcl6tm1Sdt |
| Name: |
B cell leukemia/lymphoma 6; targeted mutation 1, Louis M Staudt |
| MGI ID: |
MGI:2158439 |
| Synonyms: |
BCL-6- |
| Gene: |
Bcl6 Location: Chr16:23783802-23807602 bp, - strand Genetic Position: Chr16, 15.26 cM
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| Alliance: |
Bcl6tm1Sdt page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:39815
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129/Sv
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A genomic fragment containing coding sequences for the zinc finger DNA binding domain was replaced with a neomycin selection cassette. Western blot analysis on spleen cells derived from homozygous mice demonstrated that no detectable protein was produced from this allele.
(J:39815)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Original: |
J:39815 Dent AL, et al., Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science. 1997 Apr 25;276(5312):589-92 |
| All: |
26 reference(s) |
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Analysis Tools
