Ikzf1tm2Kge
Targeted Allele Detail
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| Symbol: |
Ikzf1tm2Kge |
| Name: |
IKAROS family zinc finger 1; targeted mutation 2, Katia Georgopoulos |
| MGI ID: |
MGI:2158690 |
| Synonyms: |
C-, IK-, Ikaros-, Ikaros C- |
| Gene: |
Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
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| Alliance: |
Ikzf1tm2Kge page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:37317
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The gene was disrupted using neomycin resistance cassette. The vector replaced a major part of the coding region of exon 7, predicted to affect the C- terminal zinc finger involved in activation, dimerization and other protein interactions. Protein was not detected in homozygous mutant animals by immunohistochemical or Western analysis.
(J:37317)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ikzf1 Mutation: |
30 strains or lines available
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| Original: |
J:37317 Wang JH, et al., Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity. 1996 Dec;5(6):537-49 |
| All: |
39 reference(s) |
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Analysis Tools
