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Neurod4tm1Kag
Targeted Allele Detail
Summary
Symbol: Neurod4tm1Kag
Name: neurogenic differentiation 4; targeted mutation 1, Ryoichiro Kageyama
MGI ID: MGI:2158737
Synonyms: Math3-, Neurod4tm1Rka
Gene: Neurod4  Location: Chr10:130104021-130116109 bp, - strand  Genetic Position: Chr10, 77.81 cM
Alliance: Neurod4tm1Kag page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65410
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: A neomycin cassette is inserted into the second exon of the wild-type gene. Northern analysis demonstrated a lack of gene specific mRNA in homozygous mutant animals. (J:65410)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neurod4 Mutation:  24 strains or lines available
References
Original:  J:65410 Tomita K, et al., Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 2000 Oct 16;19(20):5460-72
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory