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Sema3atm1.2Tyag
Targeted Allele Detail
Summary
Symbol: Sema3atm1.2Tyag
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1.2, Takeshi Yagi
MGI ID: MGI:2158945
Synonyms: Sema3afkkix, semaphorin III/D conditional
Gene: Sema3a  Location: Chr5:13175381-13652533 bp, + strand  Genetic Position: Chr5, 4.31 cM
Alliance: Sema3atm1.2Tyag page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43443
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: This allele was generated from Sema3atm1Tyag by transient cre expression in TT-2 cells. Recombination produced three alleles, Sema3atm1.1Tyag, Sema3atm1.2Tyag and Sema3atm1.3Tyag. Sema3atm1.2 has loxP sites inserted before and after the first exon. (J:43443)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3a Mutation:  48 strains or lines available
References
Original:  J:43443 Taniguchi M, et al., Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron. 1997 Sep;19(3):519-30
All:  15 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory