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Sema3atm1.3Tyag
Targeted Allele Detail
Summary
Symbol: Sema3atm1.3Tyag
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1.3, Takeshi Yagi
MGI ID: MGI:2158946
Synonyms: semaphorin III/D knocked-in lacZ
Gene: Sema3a  Location: Chr5:13175381-13652533 bp, + strand  Genetic Position: Chr5, 4.31 cM
Alliance: Sema3atm1.3Tyag page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43443
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: This allele was generated from Sema3atm1Tyag by transient Cre expression in TT-2 cells. Recombination produced three alleles, Sema3atm1.1Tyag, Sema3atm1.2Tyag and Sema3atm1.3Tyag. The Sema3atm1.3Tyag allele has the first exon deleted and replaced by a lacZ-neo construct flanked by loxP sites. (J:43443)
Inheritance:    Not Specified
Expression
In Mice Carrying this Mutation: 43 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3a Mutation:  48 strains or lines available
References
Original:  J:43443 Taniguchi M, et al., Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron. 1997 Sep;19(3):519-30
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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