Wasltm1.1Cgn
Targeted Allele Detail
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| Symbol: |
Wasltm1.1Cgn |
| Name: |
WASP like actin nucleation promoting factor; targeted mutation 1.1, University of Cologne |
| MGI ID: |
MGI:2159338 |
| Synonyms: |
N-WASPdel, Wasltm1.1Wehl |
| Gene: |
Wasl Location: Chr6:24613804-24665008 bp, - strand Genetic Position: Chr6, 11.28 cM, cytoband A3
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| Alliance: |
Wasltm1.1Cgn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:73609
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| Parent Cell Line: |
Bruce 4 (ES Cell)
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| Strain of Origin: |
B6.Cg-Thy1a
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: This allele is a derivative of Wasltm1Wehl. Cre-mediated recombination in vivo removed exons 6-9 in the germline, eliminating the effector domains and leaving a single loxP site in place of the deleted sequence. The authors predict that splicing exon 5 to the remaining exon 10 would create a premature stop codon.
(J:73609)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Wasl Mutation: |
39 strains or lines available
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| Original: |
J:73609 Lommel S, et al., Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep. 2001 Sep;2(9):850-7 |
| All: |
1 reference(s) |
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Analysis Tools
