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Kif5btm1Noh
Targeted Allele Detail
Summary
Symbol: Kif5btm1Noh
Name: kinesin family member 5B; targeted mutation 1, Nobutaka Hirokawa
MGI ID: MGI:2159694
Synonyms: kif5B-
Gene: Kif5b  Location: Chr18:6201005-6241524 bp, - strand  Genetic Position: Chr18, 4.46 cM, cytoband A2-B1
Alliance: Kif5btm1Noh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48447
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The exon encoding the ATP-binding motif (P-loop) was replaced with pPGKneopA. Disruption of gene expression was verified by RT-PCR and immunoblotting. (J:48447)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif5b Mutation:  61 strains or lines available
References
Original:  J:48447 Tanaka Y, et al., Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell. 1998 Jun 26;93(7):1147-58
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory