Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Mx1-cre)1Cgn
Name:	transgene insertion 1, University of Cologne
MGI ID:	MGI:2176073
Synonyms:	Mx1-Cre, Mx1cre, Mx-Cre, MxCre, Mx-Cre 31, MxCreTg, Tg(Mx1-cre)hemi
Transgene:	Tg(Mx1-cre)1Cgn  Location: unknown  Genetic Position: Chr10, Syntenic
Alliance:	Tg(Mx1-cre)1Cgn page

Strain of Origin:

(C57BL/6J x CBA/J)F2

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    interferon or polyinosinic-polycytidylic acid Mutation:    Insertion   Tg(Mx1-cre)1Cgn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Mx1   Mutation details: This transgene expresses Cre recombinase under the control of an inducible Mx1 promoter, which is silent in healthy mice, and active in the liver and in lymphocytes after induction with IFN or pI-pC. The construct also contains a 2.1 kb fragment from the human growth hormone gene. (J:67927)

Activity:	Tissue activity of this recombinase allele
Driver:	Mx1 (species not specified) Summary of all recombinase alleles driven by Mx1. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(Mx1-cre)1Cgn

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 7 strains available      Cell Lines: 0 lines available

Original:	J:67927 Kuhn R, et al., Inducible gene targeting in mice. Science. 1995 Sep 8;269(5229):1427-9
All:	1337 reference(s)