Tg(Col2a1-cre)10Amc
Transgene Detail
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| Symbol: |
Tg(Col2a1-cre)10Amc |
| Name: |
transgene insertion 10, Andrew P McMahon |
| MGI ID: |
MGI:2176264 |
| Synonyms: |
Col2-Cre, Col2-Cre10, CRE 10 |
| Transgene: |
Tg(Col2a1-cre)10Amc Location: unknown
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| Alliance: |
Tg(Col2a1-cre)10Amc page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Col2a1-cre)10Amc expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Col2a1 |
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Mutation details: This transgene expresses Cre recombinase under the control of the collagen II (Col2a1) promoter, which directs expression in all cartilagenous structures at E12.5, as well as the facial mesenchyme and the CNS. At E13.5, Cre-recombinase activity is detected in the skeletal structures of the developing appendicular, axial and cranial skeleton, such as long bones of limbs, ribs, vertebrae and skull base, as well as in the epithelial cells of kidney, pancreas, lungs, intestine and ovary.
(J:73071, J:140779)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Col2a1
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:73071 Long F, et al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108 |
| All: |
10 reference(s) |
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Analysis Tools
