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Arnttm1Gonz
Targeted Allele Detail
Summary
Symbol: Arnttm1Gonz
Name: aryl hydrocarbon receptor nuclear translocator; targeted mutation 1, Frank Gonzalez
MGI ID: MGI:2176696
Synonyms: Arntflox, ARNT flox, Arnt-floxed, Arntflox(neo), Hif-1betafl
Gene: Arnt  Location: Chr3:95341699-95404551 bp, + strand  Genetic Position: Chr3, 40.74 cM
Alliance: Arnttm1Gonz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64967
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A loxP flanked neomycin resistance cassette was inserted 5' to exon 6 and a single loxP site was inserted 3' to exon 6. (J:64967)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:  65 strains or lines available
References
Original:  J:64967 Tomita S, et al., Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1alpha. Mol Endocrinol. 2000 Oct;14(10):1674-81
All:  31 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory