Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Tg(Ckmm-cre)1Lrsn Name: transgene insertion 1, Nils-Goran Larsson MGI ID: MGI:2177173 Synonyms: Ckm-cre, Ckmm-cre, MCK-cre Transgene: Tg(Ckmm-cre)1Lrsn  Location: unknown  Genetic Position: Chr10, Syntenic Alliance: Tg(Ckmm-cre)1Lrsn page

Heart histology of Tfamtm1Lrsn/Tfamtm1Lrsn Tg(Ckmm-cre)1Lrsn/0 mice Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Ckmm-cre)1Lrsn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Ckm   Mutation details: A 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of cre. Cre is active in heart and skeletal muscle starting approximately at embryonic day 13. (J:51964)

Activity:	Tissue activity of this recombinase allele
Driver:	Ckm (species not specified) Summary of all recombinase alleles driven by Ckm.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:51964 Wang J, et al., Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet. 1999 Jan;21(1):133-7
All:	32 reference(s)