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Hhextm1Rbe
Targeted Allele Detail
Summary
Symbol: Hhextm1Rbe
Name: hematopoietically expressed homeobox; targeted mutation 1, Rosa Beddington
MGI ID: MGI:2177762
Synonyms: Hex-, HexlacZ
Gene: Hhex  Location: Chr19:37423289-37429179 bp, + strand  Genetic Position: Chr19, 32.28 cM, cytoband D1
Alliance: Hhextm1Rbe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62027
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    An IRES-lacZ-neo cassette replaced the first three exons of the endogenous locus. (J:62027)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 38 assay results
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hhex Mutation:  17 strains or lines available
References
Original:  J:62027 Martinez Barbera JP, et al., The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development. 2000 Jun;127(11):2433-45
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory