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Asb1tm1Wehi
Targeted Allele Detail
Summary
Symbol: Asb1tm1Wehi
Name: ankyrin repeat and SOCS box-containing 1; targeted mutation 1, Walter and Eliza Hall Institute of Medical Research
MGI ID: MGI:2178847
Synonyms: Asb-1 -
Gene: Asb1  Location: Chr1:91468266-91487311 bp, + strand  Genetic Position: Chr1, 46.19 cM
Alliance: Asb1tm1Wehi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71266
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 3 and most of exon 2 were replaced by a BetaGal-PGK-neo cassette, in which the BetaGal coding region was fused in frame to the third codon of exon 2. Northern analysis from multiple tissues confirmed the lack of endogenous transcript. (J:71266)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asb1 Mutation:  26 strains or lines available
References
Original:  J:71266 Kile BT, et al., Functional analysis of Asb-1 using genetic modification in mice. Mol Cell Biol. 2001 Sep;21(18):6189-97
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory