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Fgf18tm1Sjt
Targeted Allele Detail
Summary
Symbol: Fgf18tm1Sjt
Name: fibroblast growth factor 18; targeted mutation 1, Shinji Takada
MGI ID: MGI:2179607
Synonyms: Fgf18-
Gene: Fgf18  Location: Chr11:33067430-33097400 bp, - strand  Genetic Position: Chr11, 19.21 cM
Alliance: Fgf18tm1Sjt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75880
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details: Exon 3 was disrupted by insertion of a lacZneo cassette via homologous recombination. Homozygous mutant embryos at E9.5-E18.5 were identified by PCR analysis. (J:75880)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 25 assay results
In Structures Affected by this Mutation: 12 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf18 Mutation:  10 strains or lines available
References
Original:  J:75880 Ohbayashi N, et al., FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory