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Tg(Cga-cre)3Sac
Transgene Detail
Summary
Symbol: Tg(Cga-cre)3Sac
Name: transgene insertion 3, Sally A Camper
MGI ID: MGI:2179995
Synonyms: alphaGSU-cre, S3, TgN(Cga-cre)S3Sac
Transgene: Tg(Cga-cre)3Sac  Location: unknown  
Alliance: Tg(Cga-cre)3Sac page
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Cga-cre)3Sac expression driven by 1 gene
 
Mutation detailsThis transgene expresses Cre recombinase under the control of a mouse glycoprotein hormone alpha-subunit (Cga) gene. This promoter is active in the pituitary primordium beginning at embryonic day 9.5. Cre recombinase expression is detected in the anterior and intermediate lobes of the pituitary gland, in cardiac, and in skeletal muscle. Low to no level of expression is detected in the posterior pituitary, lungs, kidneys, brain, adrenal glands, and gonads. (J:66897)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cga (mouse)
Summary of all recombinase alleles driven by Cga.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Hemizygous transgenic mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities.
References
Original:  J:66897 Cushman LJ, et al., Cre-mediated recombination in the pituitary gland. Genesis. 2000 Nov-Dec;28(3-4):167-74
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory