Foxl1<tm1Hfk> Targeted Allele Detail MGI Mouse (MGI:2180191)

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Foxl1^tm1Hfk
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Foxl1^tm1Hfk
Name:	forkhead box L1; targeted mutation 1, Hiroshi Fukamachi
MGI ID:	MGI:2180191
Synonyms:	Fkh6-, Foxl1-
Gene:	Foxl1 Location: Chr8:121854679-121857383 bp, + strand Genetic Position: Chr8, 70.34 cM
Alliance:	Foxl1^tm1Hfk page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:76379
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutation:		Insertion
		Mutation details: The gene was disrupted by insertion of a lacZ-polyA-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant mice was confirmed via RNase protection assay. (J:76379)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Foxl1 Mutation:	12 strains or lines available

References

Original:	J:76379 Fukamachi H, et al., Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells. Biochem Biophys Res Commun. 2001 Feb 2;280(4):1069-76
All:	4 reference(s)

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