Cav2tm1Mls
Targeted Allele Detail
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| Symbol: |
Cav2tm1Mls |
| Name: |
caveolin 2; targeted mutation 1, Michael P Lisanti |
| MGI ID: |
MGI:2180372 |
| Synonyms: |
Cav-2- |
| Gene: |
Cav2 Location: Chr6:17281184-17289114 bp, + strand Genetic Position: Chr6, 7.72 cM, cytoband A2
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| Alliance: |
Cav2tm1Mls page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:75490
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| Parent Cell Line: |
WW6 (ES Cell)
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| Strain of Origin: |
STOCK 129/Sv and C57BL/6J and SJL
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 and 2 and part of the promoter region were replaced with a neo resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of heart, adipose, and lung tissue.
(J:75490)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Cav2 Mutation: |
18 strains or lines available
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| Original: |
J:75490 Razani B, et al., Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol. 2002 Apr;22(7):2329-44 |
| All: |
11 reference(s) |
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Analysis Tools
