About   Help   FAQ
Tcratm1Mjo
Targeted Allele Detail
Summary
Symbol: Tcratm1Mjo
Name: T cell receptor alpha chain; targeted mutation 1, Michael J Owen
MGI ID: MGI:2180883
Synonyms: Calpha-, Tcralpha-, TCRalpha, TCRalphae-, TCRalpha KO, Tcratm1Phi
Gene: Tcra  Location: Chr14:52665424-54461655 bp, + strand  Genetic Position: Chr14, cytoband D1-D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:1292
Parent Cell Line:  GK129 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    The Tcra-C element C1 was disrupted by the insertion of a neomycin selection cassette. (J:1292)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Tcra Mutation:  101 strains or lines available
References
Original:  J:1292 Philpott KL, et al., Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science. 1992 Jun 5;256(5062):1448-52
All:  107 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory