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Plscr1tm1Lex
Targeted Allele Detail
Summary
Symbol: Plscr1tm1Lex
Name: phospholipid scramblase 1; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:2180949
Synonyms: PLSCR1-
Gene: Plscr1  Location: Chr9:92132265-92154034 bp, + strand  Genetic Position: Chr9, 48.35 cM, cytoband E3.3
Alliance: Plscr1tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76790
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation details: Targeting was performed by Lexicon Genetics (The Woodlands, TX). No details have been provided other than that the targeting vector was constructed using a genomic DNA fragment containing exons 4 to 8 of the murine gene. Absence of gene transcript and protein product were confirmed by Northern and Western blot analysis. (J:76790)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Plscr1 Mutation:  28 strains or lines available
References
Original:  J:76790 Zhou Q, et al., Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1. Blood. 2002 Jun 1;99(11):4030-8
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory