Tnxbtm1Jbrs
Targeted Allele Detail
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| Symbol: |
Tnxbtm1Jbrs |
| Name: |
tenascin XB; targeted mutation 1, James Bristow |
| MGI ID: |
MGI:2181283 |
| Synonyms: |
Tnxb- |
| Gene: |
Tnxb Location: Chr17:34879431-34938789 bp, + strand Genetic Position: Chr17, 18.24 cM
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| Alliance: |
Tnxbtm1Jbrs page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:75812
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 2-6 were replaced with a PGK-neo-lacZ cassette via homologous recombination. The absence of mRNA and protein from skin of homozygous mutant animals was verified by Northern and Western blot analysis.
(J:75812)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tnxb Mutation: |
185 strains or lines available
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| Original: |
J:75812 Mao JR, et al., Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition. Nat Genet. 2002 Apr;30(4):421-5 |
| All: |
3 reference(s) |
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Analysis Tools
