Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Ckmm-cre)5Khn
Name:	transgene insertion 5, C Ronald Kahn
MGI ID:	MGI:2182095
Synonyms:	Ckm-cre, Ckmm-cre, Ckmm-NLS-cre, CreMck, mckCRE, MCK-cre, MCKCre+, MCK-cre5, Tg(Ckm-cre)5Khn, Tg(Ckmm-cre)1Khn
Transgene:	Tg(Ckmm-cre)5Khn  Location: unknown
Alliance:	Tg(Ckmm-cre)5Khn page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Ckmm-cre)5Khn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Ckm   Mutation details: A 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of a modified cre with an SV40 large T antigen nuclear localization signal. Expression is directed to the heart and skeletal muscle. (J:51266)

Activity:	Tissue activity of this recombinase allele
Driver:	Ckm (species not specified) Summary of all recombinase alleles driven by Ckm. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

440 assay results 20 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available

Original:	J:51266 Bruning JC, et al., A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol Cell. 1998 Nov;2(5):559-69
All:	395 reference(s)