Snai1tm1Grid
Targeted Allele Detail
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| Symbol: |
Snai1tm1Grid |
| Name: |
snail family zinc finger 1; targeted mutation 1, Tom Gridley |
| MGI ID: |
MGI:2183156 |
| Synonyms: |
Sna-, Snai1del1, Snai1null, Snatm1Grid |
| Gene: |
Snai1 Location: Chr2:167380115-167384734 bp, + strand Genetic Position: Chr2, 87.33 cM
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| Alliance: |
Snai1tm1Grid page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:72861
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 and 2 encoding amino acids 1-203, which includes the translation start codon, degenerate zinc finger 1, and zinc fingers 2 and 3 of the DNA binding domain, were replaced with a neomycin resistance gene via homologous recombination. Homozygous mutant embryos were observed by genotype analysis at E6.5-E7.5.
(J:72861)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Snai1 Mutation: |
11 strains or lines available
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| Original: |
J:72861 Carver EA, et al., The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol. 2001 Dec;21(23):8184-8 |
| All: |
10 reference(s) |
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Analysis Tools
