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Ptntm1Rau
Targeted Allele Detail
Summary
Symbol: Ptntm1Rau
Name: pleiotrophin; targeted mutation 1, Heikki Rauvala
MGI ID: MGI:2183157
Synonyms: HB-GAM -, HB-GAM2-4neo, Ptn-
Gene: Ptn  Location: Chr6:36691863-36787114 bp, - strand  Genetic Position: Chr6, 15.48 cM
Alliance: Ptntm1Rau page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:70253
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 4 were replaced with a neomycin selection cassette. Transcript was undetected via an RNA protection assay of RNA isolated from the brains of homozygous mutant mice. (J:70253)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptn Mutation:  15 strains or lines available
References
Original:  J:70253 Amet LE, et al., Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule. Mol Cell Neurosci. 2001 Jun;17(6):1014-24
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory