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Ptentm1.1Mro
Targeted Allele Detail
Summary
Symbol: Ptentm1.1Mro
Name: phosphatase and tensin homolog; targeted mutation 1.1, Silvia Marino
MGI ID: MGI:2183285
Synonyms: Ptendel
Gene: Pten  Location: Chr19:32734977-32803560 bp, + strand  Genetic Position: Chr19, 28.14 cM
Alliance: Ptentm1.1Mro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77123
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation details: This allele was generated by breeding mice carrying Ptentm1Mro with transgenic mice ubiquitously expressing cre recombinase. The expression of cre results in the excision of the floxed region containing exon 5. (J:77123)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pten Mutation:  88 strains or lines available
References
Original:  J:77123 Marino S, et al., PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development. 2002 Jul;129(14):3513-22
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory