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Tg(Otog-cre)1Ugds
Transgene Detail
Summary
Symbol: Tg(Otog-cre)1Ugds
Name: transgene insertion 1, Unite de Genetique des Deficits Sensoriels
MGI ID: MGI:2183511
Synonyms: Otog-cre, Tg(Otog-cre)1Ptt
Transgene: Tg(Otog-cre)1Ugds  Location: unknown  
Alliance: Tg(Otog-cre)1Ugds page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Otog-cre)1Ugds expression driven by 1 gene
 
Mutation details: The transgenic construct was generated by inserting sequence encoding NLS-cre recombinase into a BAC encompassing the 5' portion of the murine Otog gene. Otog is endogenously expressed in the inner ear. Cre was flanked upstream by the Otog promoter and UTR of exon 1 and downstream by the coding region of exon 1 and all of exon 2. (J:77823)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Otog (mouse)
Summary of all recombinase alleles driven by Otog.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77823 Cohen-Salmon M, et al., Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death. Curr Biol. 2002 Jul 9;12(13):1106-11
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory