Gfra3tm1Jmi
Targeted Allele Detail
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| Symbol: |
Gfra3tm1Jmi |
| Name: |
glial cell line derived neurotrophic factor family receptor alpha 3; targeted mutation 1, Jeffrey Milbrandt |
| MGI ID: |
MGI:2183558 |
| Synonyms: |
GFRalpha3tlacZ |
| Gene: |
Gfra3 Location: Chr18:34822951-34853440 bp, - strand Genetic Position: Chr18, 18.69 cM
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| Alliance: |
Gfra3tm1Jmi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:78008
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| Parent Cell Line: |
RW-4 (ES Cell)
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| Strain of Origin: |
129X1/SvJ
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutation: |
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Insertion
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Mutation details: The endogenous locus was disrupted by the insertion of a tau-lacZ cassette at the start codon by homologous recombination. A floxed neo cassette that was included in the targeting vector was excised via in vivo cre mediated recombination, leaving a single loxP site immediately downstream of the tau-lacZ sequence. Normal transcript was undetected by RT-PCR analysis of homozygous mutant mice.
(J:78008)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gfra3 Mutation: |
33 strains or lines available
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| Original: |
J:78008 Honma Y, et al., Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 2002 Jul 18;35(2):267-82 |
| All: |
3 reference(s) |
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Analysis Tools
