Hspa1atm1Msk
Targeted Allele Detail
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| Symbol: |
Hspa1atm1Msk |
| Name: |
heat shock protein 1A; targeted mutation 1, Demetrius Moskophidis |
| MGI ID: |
MGI:2183895 |
| Synonyms: |
hsp70.3- |
| Gene: |
Hspa1a Location: Chr17:35188335-35191132 bp, - strand Genetic Position: Chr17, 18.51 cM
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| Alliance: |
Hspa1atm1Msk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:72943
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Most of the coding region of the gene (codons 1-633) was replaced with an in frame lacZ floxed TK-neo cassette via homologous recombination. Southern blot and PCR genotype analysis confirmed the targeted allele in homozygous mutant animals.
(J:72943)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Hspa1a Mutation: |
24 strains or lines available
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| Original: |
J:72943 Huang L, et al., Insights into Regulation and Function of the Major Stress-Induced hsp70 Molecular Chaperone In Vivo: Analysis of Mice with Targeted Gene Disruption of the hsp70.1 or hsp70.3 Gene. Mol Cell Biol. 2001 Dec;21(24):8575-91 |
| All: |
1 reference(s) |
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Analysis Tools
