Rad54ltm1Jhjh
Targeted Allele Detail
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| Symbol: |
Rad54ltm1Jhjh |
| Name: |
RAD54 like (S. cerevisiae); targeted mutation 1, Jan H J Hoeijmakers |
| MGI ID: |
MGI:2183934 |
| Synonyms: |
mRAD54-, mRAD54307neo |
| Gene: |
Rad54l Location: Chr4:115951458-115980875 bp, - strand Genetic Position: Chr4, 53.1 cM
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| Alliance: |
Rad54ltm1Jhjh page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:39642
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A neomycin selection cassette was inserted into exon 4, upstream of approximately 90% of the protein product including the conserved motifs involved in ATPase activity. Sequence analysis showed that excision of the disrupted exon would result in a frameshift mutation. The absence of transcript and protein was determined by Northern and Western blot analysis.
(J:39642)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rad54l Mutation: |
47 strains or lines available
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| Original: |
J:39642 Essers J, et al., Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell. 1997 Apr 18;89(2):195-204 |
| All: |
23 reference(s) |
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Analysis Tools
