About   Help   FAQ
Pex5tm1Pec
Targeted Allele Detail
Summary
Symbol: Pex5tm1Pec
Name: peroxisomal biogenesis factor 5; targeted mutation 1, Peter Carmeliet
MGI ID: MGI:2384516
Synonyms: Pex52loxP, Pex5FL, Pex5flox
Gene: Pex5  Location: Chr6:124373775-124392026 bp, - strand  Genetic Position: Chr6, 59.15 cM
Alliance: Pex5tm1Pec page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75108
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: Four exons encompassing sequence encoding several tetratricopeptide repeat domains were flanked by an upstream floxed neo cassette and a downstream intronic loxP site. Transient transfection of ES cells with plasmids expressing cre resulted in the excision of the floxed neo cassette, leaving single loxP sites in the introns surrounding the four exons. (J:75108)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pex5 Mutation:  30 strains or lines available
References
Original:  J:75108 Baes M, et al., Generation of Pex5-loxP mice allowing the conditional elimination of peroxisomes. Genesis. 2002 Feb;32(2):177-8
All:  18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory