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Mrgprf Gene Detail
Summary
  • Symbol
    Mrgprf
  • Name
    MAS-related GPR, member F
  • Synonyms
    MGC:18825, MrgF
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384823
    NCBI Gene: 211577
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:144854646-144863294 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 89.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384823
 protein coding gene Chr7:144854565-144863294 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033297
 protein coding gene Chr7:150715514-150724265 (+)
A/J MGP_AJ_G0033280
 protein coding gene Chr7:146340428-146349167 (+)
AKR/J MGP_AKRJ_G0033211
 protein coding gene Chr7:150444761-150453486 (+)
BALB/cJ MGP_BALBcJ_G0033280
 protein coding gene Chr7:146100515-146109242 (+)
C3H/HeJ MGP_C3HHeJ_G0032994
 protein coding gene Chr7:150209330-150218069 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033790
 protein coding gene Chr7:156133151-156141825 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030763
 protein coding gene Chr7:147480553-147489219 (+)
CAST/EiJ MGP_CASTEiJ_G0032317
 protein coding gene Chr7:142530554-142540567 (+)
CBA/J MGP_CBAJ_G0032967
 protein coding gene Chr7:161434261-161443000 (+)
DBA/2J MGP_DBA2J_G0033121
 protein coding gene Chr7:144299015-144307799 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0033213
 protein coding gene Chr7:152273387-152282138 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033103
 protein coding gene Chr7:161969817-161981201 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033808
 protein coding gene Chr7:149407759-149416499 (+)
PWK/PhJ MGP_PWKPhJ_G0032027
 protein coding gene Chr7:137632339-137641231 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031871
 protein coding gene Chr7:136205789-136216396 (+)
WSB/EiJ MGP_WSBEiJ_G0032430
 protein coding gene Chr7:150404763-150413516 (+)



Homology
more
  • Human Ortholog
    MRGPRF, MAS related GPR family member F
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGPRF, MAS related GPR family member F
  • Synonyms
    GPR140, GPR168, MRGF, RTA
  • Links
    NCBI Gene ID: 116535
    neXtProt AC: NX_Q96AM1
    UniProt: Q96AM1

  • Chr Location
    11
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211577 NCBI Gene Model | MGI Sequence Detail 8649 C57BL/6J ±  kb
transcript NM_145379 RefSeq | MGI Sequence Detail 2006 C57BL/6  
polypeptide Q8VCJ6 UniProt | EBI | MGI Sequence Detail 343 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000001604 Mas-related G-protein coupled receptor F
    (term hierarchy)
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR026228 Mas-related G protein-coupled receptor F
    IPR026234 Mas-related G protein-coupled receptor family
  • GlyGen
    Q8VCJ6 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:246058 Kaur H, et al., Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system. Nat Commun. 2017 Jun 16;8:15700
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory