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Ube2d1 Gene Detail
Summary
  • Symbol
    Ube2d1
  • Name
    ubiquitin-conjugating enzyme E2D 1
  • Synonyms
    MGC:28550, UBCH5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384911
    NCBI Gene: 216080
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:71090810-71121048 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 36.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    863 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384911
 protein coding gene Chr10:71090810-71121092 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017343
 protein coding gene Chr10:71241362-71271683 (-)
A/J MGP_AJ_G0017320
 protein coding gene Chr10:68791054-68821422 (-)
AKR/J MGP_AKRJ_G0017281
 protein coding gene Chr10:70677153-70710499 (-)
BALB/cJ MGP_BALBcJ_G0017280
 protein coding gene Chr10:68993969-69024548 (-)
C3H/HeJ MGP_C3HHeJ_G0017104
 protein coding gene Chr10:70680313-70711563 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017738
 protein coding gene Chr10:73774644-73804947 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015428
 protein coding gene Chr10:65363806-65394147 (-)
CAST/EiJ MGP_CASTEiJ_G0016674
 protein coding gene Chr10:70837472-70869094 (-)
CBA/J MGP_CBAJ_G0017076
 protein coding gene Chr10:76649655-76686111 (-)
DBA/2J MGP_DBA2J_G0017181
 protein coding gene Chr10:68148474-68177873 (-)
FVB/NJ MGP_FVBNJ_G0017174
 protein coding gene Chr10:67315304-67346384 (-)
LP/J MGP_LPJ_G0017254
 protein coding gene Chr10:71677946-71710054 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017202
 protein coding gene Chr10:78703299-78739104 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017777
 protein coding gene Chr10:70641978-70672814 (-)
PWK/PhJ MGP_PWKPhJ_G0016458
 protein coding gene Chr10:68005404-68036491 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016241
 protein coding gene Chr10:70005863-70036126 (-)
WSB/EiJ MGP_WSBEiJ_G0016738
 protein coding gene Chr10:70590667-70625502 (-)



Homology
more
  • Human Ortholog
    UBE2D1, ubiquitin conjugating enzyme E2 D1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2D1, ubiquitin conjugating enzyme E2 D1
  • Synonyms
    E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
  • Links
    NCBI Gene ID: 7321
    neXtProt AC: NX_P51668
    UniProt: P51668

  • Chr Location
    10q21.1; chr10:58334979-58370751 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    772
  • Tissues
    12
  • cDNA Data
    52
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216080 NCBI Gene Model | MGI Sequence Detail 30239 C57BL/6J ±  kb
    transcript NM_001421283 RefSeq | MGI Sequence Detail 1518 C57BL/6  
    polypeptide P61080 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 52

      Microarray probesets 3
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 2
      Gene Ontology 12
      Phenotypes 15
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory