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Alg12 Gene Detail
Summary
  • Symbol
    Alg12
  • Name
    ALG12 alpha-1,6-mannosyltransferase
  • Synonyms
    ECM39, mannosyltransferase, MGC:29374
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385025
    NCBI Gene: 223774
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:88689448-88703498 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 44.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    438 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385025
 protein coding gene Chr15:88689447-88703521 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022208
 protein coding gene Chr15:89962089-89977692 (-)
A/J MGP_AJ_G0022167
 protein coding gene Chr15:86530025-86542924 (-)
AKR/J MGP_AKRJ_G0022142
 protein coding gene Chr15:89091904-89105866 (-)
BALB/cJ MGP_BALBcJ_G0022173
 protein coding gene Chr15:86627909-86641971 (-)
C3H/HeJ MGP_C3HHeJ_G0021943
 protein coding gene Chr15:89072377-89086432 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022618
 protein coding gene Chr15:93227460-93241524 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020143
 protein coding gene Chr15:82762672-82776217 (-)
CAST/EiJ MGP_CASTEiJ_G0021465
 protein coding gene Chr15:89857381-89871434 (-)
CBA/J MGP_CBAJ_G0021910
 protein coding gene Chr15:96389754-96403782 (-)
DBA/2J MGP_DBA2J_G0022037
 protein coding gene Chr15:85964637-85978646 (-)
FVB/NJ MGP_FVBNJ_G0022016
 protein coding gene Chr15:85044708-85059226 (-)
LP/J MGP_LPJ_G0022108
 protein coding gene Chr15:90114391-90130446 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022036
 protein coding gene Chr15:100835064-100849395 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022633
 protein coding gene Chr15:89113814-89128018 (-)
PWK/PhJ MGP_PWKPhJ_G0021206
 protein coding gene Chr15:86026525-86040151 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021040
 protein coding gene Chr15:88860088-88873916 (-)
WSB/EiJ MGP_WSBEiJ_G0021514
 protein coding gene Chr15:89604266-89619471 (-)



Homology
more
  • Human Ortholog
    ALG12, ALG12 alpha-1,6-mannosyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALG12, ALG12 alpha-1,6-mannosyltransferase
  • Synonyms
    CDG1G, ECM39, hALG12, PP14673
  • Links
    NCBI Gene ID: 79087
    neXtProt AC: NX_Q9BV10
    UniProt: Q9BV10

  • Chr Location
    22q13.33; chr22:49859311-49918438 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ALG12 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    24
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223774 NCBI Gene Model | MGI Sequence Detail 14051 C57BL/6J ±  kb
transcript NM_001416017 RefSeq | MGI Sequence Detail 2396 C57BL/6  
polypeptide Q8VDB2 UniProt | EBI | MGI Sequence Detail 486 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 5
References
more
  • Summaries
    All 54
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 30
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory