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Lhx1tm2.1Bhr
Targeted Allele Detail
Summary
Symbol: Lhx1tm2.1Bhr
Name: LIM homeobox protein 1; targeted mutation 2.1, Richard R Behringer
MGI ID: MGI:2385716
Synonyms: Lhx1fx2, Lhx1loxP, Lim1flox, Lim1-floxed
Gene: Lhx1  Location: Chr11:84409110-84416361 bp, - strand  Genetic Position: Chr11, 51.31 cM
Alliance: Lhx1tm2.1Bhr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75126
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: The entire coding region of the endogenous gene was left flanked by single loxP sites after the neo cassette inserted downstream of the stop codon was excised via the breeding of mice carrying Lhx1tm2Bhr with transgenic mice expressing cre recombinase via the ubiquitous CMV promoter. (J:75126)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 71 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 13 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx1 Mutation:  22 strains or lines available
References
Original:  J:75126 Kwan KM, et al., Conditional inactivation of Lim1 function. Genesis. 2002 Feb;32(2):118-20
All:  22 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory