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Tg(Ucp1-cre)14Bnto
Transgene Detail
Summary
Symbol: Tg(Ucp1-cre)14Bnto
Name: transgene insertion 14, Manuel Benito
MGI ID: MGI:2385804
Synonyms: UCP1-cre, UCP-1-Cre
Transgene: Tg(Ucp1-cre)14Bnto  Location: unknown  
Alliance: Tg(Ucp1-cre)14Bnto page
Transgene
origin
Strain of Origin:  FVB/NJ
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Ucp1-cre)14Bnto expression driven by 1 gene
 
Mutation details: This transgene utilized 8.4 kb of 5' untranslated sequence encompassing regulatory elements of the brown adipose tissue specific Ucp1 promoter. In addition to the promoter, a portion of exon 3 and all of exons 4, 5, and 6 from the Ucp1 gene were inserted downstream of the cre recombinase transgene. (J:72231)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ucp1 (species not specified)
Summary of all recombinase alleles driven by Ucp1.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:72231 Guerra C, et al., Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance. J Clin Invest. 2001 Oct;108(8):1205-13
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory