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Kat2atm1Roth
Targeted Allele Detail
Summary
Symbol: Kat2atm1Roth
Name: K(lysine) acetyltransferase 2A; targeted mutation 1, Sharon Y Roth
MGI ID: MGI:2386279
Synonyms: Gcn5-, Gcn5delta, Gcn5l2-
Gene: Kat2a  Location: Chr11:100595572-100603291 bp, - strand  Genetic Position: Chr11, 63.53 cM
Alliance: Kat2atm1Roth page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65002
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The entire coding region of the endogenous gene was replaced with a cassette containing lacZ and neo. Transcript was undetected in homozygous mutant embryos via whole mount in situ hybridization. (J:65002)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
In Structures Affected by this Mutation: 17 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat2a Mutation:  40 strains or lines available
References
Original:  J:65002 Xu W, et al., Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory