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Tg(Nes-cre)3Wme
Transgene Detail
Summary
Symbol: Tg(Nes-cre)3Wme
Name: transgene insertion 3, Werner Muller
MGI ID: MGI:2386551
Synonyms: bal3, balancer3, NesI2Crec-1
Transgene: Tg(Nes-cre)3Wme  Location: unknown  
Alliance: Tg(Nes-cre)3Wme page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nes-cre)3Wme expression driven by 1 gene
 
Mutation detailsThe transgenic construct contained a nestin promoter followed by cre recombinase sequence adjoined to a nuclear localization signal. Intron 2 of the nestin gene was included downstream of a polyadenylation signal. While the endogenous nestin promoter is CNS-specific, Southern blot analysis showed the ubiquitous expression of cre in transgenic mice. (J:67926)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nes (species not specified)
Summary of all recombinase alleles driven by Nes.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:67926 Betz UA, et al., Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination. Curr Biol. 1996 Oct 1;6(10):1307-16
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory