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Tg(Col2a1-cre)1Rsjo
Transgene Detail
Summary
Symbol: Tg(Col2a1-cre)1Rsjo
Name: transgene insertion 1, Randall S Johnson
MGI ID: MGI:2386649
Synonyms: colIIcre
Transgene: Tg(Col2a1-cre)1Rsjo  Location: unknown  
Alliance: Tg(Col2a1-cre)1Rsjo page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Col2a1-cre)1Rsjo expression driven by 1 gene
 
Mutation details: The cre coding region along with a nuclear localization and polyadenylation signals was adjoined to the rat collagen 2a1 promoter and enhancer. The rat Col2a promoter was shown to drive expression in cartilage. (J:72709)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Col2a1 (rat)
Summary of all recombinase alleles driven by Col2a1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:72709 Schipani E, et al., Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 2001 Nov 1;15(21):2865-76
All:  11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory