Satb1tm1Kos
Targeted Allele Detail
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| Symbol: |
Satb1tm1Kos |
| Name: |
special AT-rich sequence binding protein 1; targeted mutation 1, Terumi Kohwi-Shigematsu |
| MGI ID: |
MGI:2386676 |
| Gene: |
Satb1 Location: Chr17:52043215-52140318 bp, - strand Genetic Position: Chr17, 26.81 cM
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| Alliance: |
Satb1tm1Kos page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:61085
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 10.9 kb region containing exons 1 through 5 was replaced by a neomycin selection cassette inserted at the endogenous locus via homologous recombination. The deleted exons encoded 213 amino acids, including the intitiator methionine. RT-PCR and Western blot analyses of thymus extracts showed an absence of endogenous transcript and protein in homozygous mutant mice.
(J:61085)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Satb1 Mutation: |
48 strains or lines available
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| Original: |
J:61085 Alvarez JD, et al., The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev. 2000 Mar 1;14(5):521-35 |
| All: |
9 reference(s) |
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Analysis Tools
