Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Fabp4-cre)1Rev
Name:	transgene insertion 1, Ronald M Evans
MGI ID:	MGI:2386686
Synonyms:	aP2-CRE, aP2-Cre1, aP2-CreSI, FABP4-Cre
Transgene:	Tg(Fabp4-cre)1Rev  Location: unknown
Alliance:	Tg(Fabp4-cre)1Rev page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Fabp4-cre)1Rev expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Fabp4   Mutation details: Sequence encoding cre recombinase was adjoined to the Fabp4 promoter, which is active in white and brown adipose tissue. Northern blot analysis and a functional assay showed the transgene to be abundantly expressed in brown and white adipose tissue. Significant expression was not detected in other tissues including skeletal muscle, liver, and heart. (J:73557, J:88210)

Activity:	Tissue activity of this recombinase allele
Driver:	Fabp4 (species not specified) Summary of all recombinase alleles driven by Fabp4. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

17 assay results 5 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:73557 Barak Y, et al., Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8
All:	222 reference(s)