Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Myh6-cre)2182Mds
Name:	transgene insertion 2182, Michael D Schneider
MGI ID:	MGI:2386742
Synonyms:	alphaMhc-Cre, alpha-MHC-Cre+, alphaMyHC-Cre, MCH-cre, MHCalphaCre, MHCcre, MHC-Cre, Tg(Myhca-cre)2182Mds
Transgene:	Tg(Myh6-cre)2182Mds  Location: unknown
Alliance:	Tg(Myh6-cre)2182Mds page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Myh6-cre)2182Mds expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Myh6   Mutation details: The transgenic construct contained the Myh7 3' untranslated region, the Myhca promoter, Myhca noncoding exons 1 and 2, and the exon 3 splice acceptor site 180 bp upstream and driving the expression of the cre recombinase sequence. The Myhca promoter drives expression in cardiac tissue. (J:67908)

Generation of the Rhebtm1.1Otsu allele

Activity:	Tissue activity of this recombinase allele
Driver:	Myh6 (species not specified) Summary of all recombinase alleles driven by Myh6. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

134 assay results 31 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available

Original:	J:67908 Agah R, et al., Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest. 1997 Jul 1;100(1):169-79
All:	493 reference(s)