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Cd55tm1Song
Targeted Allele Detail
Summary
Symbol: Cd55tm1Song
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1, Wen-Chao Song
MGI ID: MGI:2387405
Synonyms: Daf-, Daf1-
Gene: Cd55  Location: Chr1:130366764-130390481 bp, - strand  Genetic Position: Chr1, 56.89 cM
Alliance: Cd55tm1Song page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52968
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: Exons 1, 2 and 3, encoding the first and second short consensus repeats, were replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice by Northern blot analysis. (J:52968)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd55 Mutation:  39 strains or lines available
References
Original:  J:52968 Sun X, et al., Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):628-33
All:  29 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory