Wnt7b<tm1Parr> Targeted Allele Detail MGI Mouse (MGI:2387443)

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Wnt7b^tm1Parr
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Wnt7b^tm1Parr
Name:	wingless-type MMTV integration site family, member 7B; targeted mutation 1, Brian A Parr
MGI ID:	MGI:2387443
Synonyms:	Wnt7b^-, Wnt7b^D3, Wnt7b^D3-4
Gene:	Wnt7b Location: Chr15:85419638-85466022 bp, - strand Genetic Position: Chr15, 40.39 cM
Alliance:	Wnt7b^tm1Parr page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:71583
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: The gene was disrupted by replacement of part of exon 3 and part of intron 3 with a neomycin resistance cassette via homologous recombination. (J:71583)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	13 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Wnt7b Mutation:	17 strains or lines available

References

Original:	J:71583 Parr BA, et al., Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15;237(2):324-32
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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