Tg(CMV-cre/ERT)1Ipc
Transgene Detail
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| Symbol: |
Tg(CMV-cre/ERT)1Ipc |
| Name: |
transgene insertion 1, I Pierre Chambon |
| MGI ID: |
MGI:2387570 |
| Synonyms: |
CMV-cre, CMV-Cre-ERT, CMV-CRE-ER-Tx, Cre-ERT, CRE-ER-Tx, Tg(CMV-cre/ESR1)1Ipc |
| Transgene: |
Tg(CMV-cre/ERT)1Ipc Location: unknown
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| Alliance: |
Tg(CMV-cre/ERT)1Ipc page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(CMV-cre/ERT)1Ipc expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| virus |
CMV |
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Mutation details: The transgenic construct encodes a tamoxifen-dependent cre recombinase. The cre recombinase coding region was joined to a sequence encoding the ligand-binding domain of the human estrogen receptor with glycine to arginine missense mutation at position 521. This substitution enables the domain to bind to tamoxifen while ablating the estradiol binding ability. The transgene was driven by the CMV promoter.
(J:79245)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CMV
(virus)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:79245 Feil R, et al., Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10887-90 |
| All: |
23 reference(s) |
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Analysis Tools
