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Ptf1atm1(cre)Cvw
Targeted Allele Detail
Summary
Symbol: Ptf1atm1(cre)Cvw
Name: pancreas specific transcription factor, 1a; targeted mutation 1, Christopher VE Wright
MGI ID: MGI:2387804
Gene: Ptf1a  Location: Chr2:19450474-19452312 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Alliance: Ptf1atm1(cre)Cvw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78710
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Ptf1atm1(cre)Cvw expression driven by 1 gene
 
Mutation details: The entire coding region was replaced with a cassette containing cre recombinase and a floxed neomycin resistance gene by homologous recombination. (J:78710)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ptf1a (mouse)
Summary of all recombinase alleles driven by Ptf1a.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  31 strains or lines available
References
Original:  J:78710 Kawaguchi Y, et al., The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet. 2002 Sep;32(1):128-34
All:  19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory