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Mixl1tm1.1Robb
Targeted Allele Detail
Summary
Symbol: Mixl1tm1.1Robb
Name: Mix paired-like homeobox; targeted mutation 1.1, Lorraine Robb
MGI ID: MGI:2387829
Synonyms: Mixl1deltaneo
Gene: Mixl1  Location: Chr1:180520608-180524599 bp, - strand  Genetic Position: Chr1, 84.46 cM
Alliance: Mixl1tm1.1Robb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77443
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation details: The floxed neo cassette was excised from Mixl1tm1Robb via in vivo cre mediated recombination. The previously inserted GFP sequence remained in place of the coding region of exon 1. (J:77443)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mixl1 Mutation:  20 strains or lines available
References
Original:  J:77443 Hart AH, et al., Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory